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Red Barn Technology Group provides HPC solutions, technology and hardware for a diverse range of clients, including leaders in Education, Research and Industry. Below are just a few of Red Barn HPC’s current and past customers:

Cornell University’s Computational Biology Service Unit uses Red Barn compute clusters to provide research, software and hardware support for computational biology applications.

The Customer: Dr. Jaroslaw Pillardy @ CBSU, Bioinformatics Facility

Computational Biology Service Unit is Cornell University’s core facility for computational biology and bioinformatics. CBSU’s mission is to provide research and computational support for life sciences research through training and research collaboration; and to bring advanced computational tools and techniques to life sciences investigators.

Since 2001, CBSU has been developing and maintaining a web-based interface to provide scientists in the field user-friendly and affordable access to a high performance computing environment. Through the project BioHPC, researchers can log in from any computer and submit jobs to a suite of computational biology applications running on the CBSU compute clusters. Using the advanced computing resources available through BioHPC Computing Lab and BioHPC Web portal “[biologists] don’t need to deal with parallel job submission, queues, clusters: knowing the application, parameters and input is all that is required.”

The System: “…new large memory machines from Red Barn are used for memory intensive applications in bioinformatics…”

To keep up with CBSU’s specialized computational demands, the unit’s facility utilizes a platform based on Red Barn HPC servers each with 64 cores, 512GB of memory and 18TB of local storage.

CBSU Director and Senior Research Associate since 2004, Jaroslaw Pillardy details some of the specific uses of the compute clusters: “The new large memory machines from Red Barn are used for memory intensive applications in bioinformatics; the most demanding being de novo genome assembly from next generation sequencing data. This application becomes more common with the advance of sequencing technologies and large memory machines are essential there. The Red Barn servers are also being used for wide array of other computations related to genetic diversity studies with next generation sequencing data. In particular, the machines are used in our collaborative projects: genetic architecture of maize and teosinte; a systems approach to the development and function of C4 photosynthesis; high-resolution map of recombination in maize; accelerating grape cultivar improvement via phenotyping centers and next generation markers, and many other small projects.”

Why Red Barn: Red Barn has been building HPC products for over 15 years, and has the experience and expertise to provide a solution for any size project.

Dr. Pillardy writes “Red Barn is our preferred source of high-end computing servers since it offers very affordable and highly configurable systems, coupled with excellent support in the server design stage. The people from Red Barn are very knowledgeable, friendly and helpful with all our questions and concerns. As a customer I feel personal connection with the company. We recommended Red Barn to several groups from Cornell University, all the systems purchased by us and others perform very well, and a few small problems were addressed fast and professionally by Red Barn staff.”

At Red Barn, we approach each project individually and design systems tailored for the customer’s specfic requirements. We work with our clients during every step from concept to completion to make sure every objective is met.

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Red Barn HPC servers enable research to uncover the causes of autism

 

The Customer: Cognitive Genomics Group @ Cold Spring Harbor Laboratory

Cold Spring Harbor Laboratory on the North Shore of Long Island runs a world-renowned program in Genomics Research, the study of individual genomes. A substantial genomics effort funded largely by the Simons Foundation underway at CSHL is focused on autism. These CSHL scientists are developing and employing new technologies and software to scan and analyze genomes in an effort to understand the genetics of this disorder.

A recent study focused on small-scale de novo mutations — changes in DNA as small as a single DNA “letter” relative to the normal sequence, and small insertions or deletions as large as 10 or 15 letters. The research team at CSHL found a striking link between the Fragile-X gene and mutations that cause autism.

This autism research project utilizes some standard DNA sequencing analysis tools such as BWA for sequence mapping, GATK, SAMtools, etc, and then a number of custom programs for genotyping and copy-number analysis.

The System: The data intensive research conducted at CSHL required a flexible scalable solution.

The Red Barn HPC systems that are being utilized for this research include 320 processing cores (Xeon X5690 and Xeon E5 2690), 4,352Gb of memory, and a Petabyte of local storage, accessible directly and via a parallel file system and interconnected with 10G networking. This much power across only 24 nodes enables the researchers to quickly process the large amounts of data necessary to enable their research.

Why Red Barn: At Red Barn we are focused on customer satisfaction and long-term business relationships. Our commitment to our clients is to stand behind our products 100%.

Peter Andrews, Researcher at CSHL writes, “CSHL has worked with Red Barn since 2006, we chose Red Barn because of their price, and have stayed customers because of their service. We have experienced minimal failures, substantial up-time and system performance within our expectations.”

A true end-to-end HPC solutions company, Red Barn’s experts are available to advise on the latest technology and upgrade options as needed for CSHL to add to their computing power.

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Other Featured Clients

Whitehead Institute at MIT Central Florida University
Binghamton University Hamilton College
Duke University Syracuse University
University of Maryland Lockheed Martin
University of Texas Emhart Glass
City College of New York Diamond Visionics
University of Northern Iowa University of New England
Allergen Inc. Algo Engineering
University of Iowa Air Force Research Lab
Integral Molecular BAE Systems

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